MEDICATION QUIZ #1

Answers can be found at the end

1) The proper pharmacokinetic sequence of a drug is:
a) Absorption, metabolism, distribution, excretion
b) Absorption, distribution, metabolism, excretion
c) Distribution, absorption, metabolism, excretion
d) Distribution, metabolism, absorption, excretion

2) Drugs that pass rapidly through the GI membrane include:
a) Lipid-soluble & ionized
b) Water soluble & ionized
c) Lipid-soluble & non-ionized
d) Water soluble & non-ionized

3) Factors that commonly affect drug action:
a) Stress, hunger, weather, pH of drug
b) Poor circulation, hunger, stress, BMI
c) Poor circulation, pain, stress, hunger, fasting
d) BMI, pH of drug, stress, poor circulation

4) Enteric coated tablets are absorbed where?
a) Stomach
b) Intestine
c) Mouth
d) Esophagus 

5) Food may have what effect on drug dissolution & absorption?
a) Enhances
b) Interferes with effect
c) Does not affect
d) Catalytic

6) The major site of drug metabolism is:
a) Kidney
b) Liver
c) Skin
d) lung

7) The serum half-life of a drug is the time required
a) For half of the drug dose to be absorbed
b) After absorption for half of the drug to be eliminated
c) For half the drug dose to be completely distributed
d) For the drug to be totally effective

8) Drugs with a half-life of 34-30 hours would probably be administered on a schedule of
a) TID
b) BID
c) QD
d) QOD

9) The Pt has a renal disorder with a Creatinine clearance of 40ml/min – You would expect the dosage to be:
a) Discontinued
b) Increased
c) Decreased
d) Doubled

10) A drug must be ____ for elimination through the kidneys to be possible.
a) Water-soluble
b) Lipid-soluble
c) Protein bound
d) One with a long half life 

11. You are to administer four tablets with dosage strength of 0.04 mg each. What total dosage are you giving?
(a) 0.40
(b) 0.16
(c) 0.80

12. Convert the following metric measures: 2000g = ? kg
(a) 90.4 kg
(b) 2 kg
(c) 4.4kg

13. Convert the following metric measures: 0.9 mL = ? cc
(a) 0.9 cc
(b) 90 cc
(c) 900cc

14. What is the drip rate in for 75 mL/hr infusion if a microdrip is used?
(a) 60 gtt/min
(b) 100gtt/min
(c) 75gtt/min

15. The order is for 500 mL NS / 8 hr. The set is calibrated at 15 gtt/mL. What is the drip rate?
(a) 50 gtt/min
(b) 30 gtt/min
(c) 16 gtt/min

16. Have on Hand: Tobramycin 60 mg per 6 mL

Order Tobramycin 30 mg
How many mL/cc is needed?

17. 

Have on Hand: Sodium Injection 5000 USP Units/mL
Order 2500 U
How many mL/cc is needed?

18. The order is 50 mL of a piggyback antibiotic / 1 hour. The set is a microdrip.
(a) 50 gtt/min
(b) 60 gtt/min
(c) 70 gtt/min

19. A Pt in heart block has Isuprel ordered at 4 mcg/min. The solution available is 1 mg / 250 mL D5W. What is the mL/hr flow rate?
(a) 60mL/°
(b) 55mL/°
(c) 50ml/°

20. A major drug-food interaction occurs between MAO inhibitors & foods rich in what of the following?
(a) Fiber
(b) Caffeine
(c) Tyramine
(d) Acetylcholine

Answers: 

1. B, 2. C, 3. C, 4. B, 5. B, 6. B, 7. B, 8. C, 9. C, 10. A

11. B 12. B 13. A 14. C 15. C 16. 3ML 17. 0.5ML 18. A 19. A 20. C